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KMID : 1191520180230010033
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Journal of Korean Traditional Oncology
2018 Volume.23 No. 1 p.33 ~ p.43
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A Case Report of Cyclophosphamide plus Doxorubicin-induced Side effects in Patient with Both Sides Breast Cancer Treated with Integrative Medicine Therapy Including Pharmacopuncture
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Kim Min-Serh
Jung Yu-Jin
Hong Sang-Hoon
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Abstract
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Objectives: To observe the mitigating effects of a Traditional Korean Medicine(TKM) treatment program especially including pharmacopuncture, with Cyclophosphamide and doxorubicin chemotherapy on a both sides breast cancer patient.
Methods: AA 74 year-old female patient diagnosed with both sides breast cancer (Right) pT1bpN0M0, (Left) pT1cpN1Mx was admitted to hospital of Dong-eui university in May of 2017. She received Cyclophosphamide and Doxorubicin from May 31st to August 2nd, 2017 followed by TKM treatment consisting of herbal medicine, acupuncture, moxibustion and
pharmacopuncture (Trionycis Carapax, Non-toxic Bee Venom, and Cultivated Wild Ginseng Extract) for a period of almost 4 months, from May 13th to August 19th, 2017. Symptoms were evaluated by the grade of chief complaints refer to Common Terminology Criteria for Adverse Events (CTCAE) and Eastern Cooperative Oncology Group (ECOG).
Results: TKM including pharmacopuncture alleviated chemotherapy-induced nausea, fatigue, joint pain, diarrhea, insomnia.
Conclusions: This case study potentiates TKM with pharmacopuncture’s significant efficacy in aiding breast cancer patients suffering from Cyclophosphamide plus Doxorubicin induced adverse effects. Further research should take place for clear understanding of the exact amount of dosage and safety. Moreover it must be accompanied by long-term follow up researches.
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KEYWORD
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Cyclophosphamide, Doxorubicin, Breast cancer, Pharmacopuncture, Side effects
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